International Agency for Research on Cancer (IARC) - Summaries & Evaluations
5-(MORPHOLINOMETHYL)-3-[(5-NITROFURFURYLIDENE)-
AMINO]-2-OXAZOLIDINONE
VOL.: 7 (1974) (p. 161)
dl-Form
CAS No.: 139-91-3
l-Form
CAS No.: 3795-88-8
dl-Form hydrochloride
CAS No.: 13146-28-6
4. Comments on Data Reported and Evaluation
5.1 Animal carcinogenicity data
5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-2-oxazolidinone
is carcinogenic in rats following oral administration of its
hydrochloride. It produced mainly mammary carcinomas and lymphoblastic
lymphomas. No other species or routes of administration were tested.
5.2 Human carcinogenicity data
No case reports or epidemiological studies were available to the
Working Group.
Subsequent evaluation: Suppl. 7 (1987) (p. 67: Group 2B)
For definition of Groups, see Preamble Evaluation.
Synonyms for the dl-Form
- Altabactina
- Altafur
- Biofurin
- Donafur
- F-150
- Furaltadone
- Furaltadone tartrate
- Furalton
- Furamidone
- Furasol
- Furazol INE
- Furazolin
- Furazoline
- Furfural Piper
- Furitale
- Furlate
- Furlidon
- Furmethonol
- Furmetox
- Fur-Novo
- Germicina
- Ibifur
- Medifuran
- Megafur
- (+/-)5-Methyl morpholino-3-[amino(5-nitrofurfurylidene)]-2-oxazolidinone
- 5-Morpholinomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidinone
- 5-(N-Morpholinomethyl)-3-(nitrofurfurylideneamino)-2-oxazolidinone
- (+/-)-5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-2-oxazolidinone
- 5-(4-Morpholinomethyl)-3-(5-nitrofurfurylideneamino)-2-oxazolidinone
- 5-(4-Morpholinomethyl)-3-(5-nitro-2-furfurylideneamino)-2-oxazolidinone
- 5-(4-Morpholinylmethyl)-3-{[(5-nitro-2-furanyl)methylene]-amino}-2-oxazolidinone
- Nitrofuraltadone
- 3-(5-Nitro-2-furfurylideneamino)-5-(4-morpholinomethyl)-2-oxazolidinone
- N-(5-Nitro-2-furfurylidene)-3-amino-5-(N'-morpholinylmethyl)-2-oxazolidinone
- Neofuran
- NF 260
- Nifadone
- Nitraldone
- Nitrofur
- Nitrofurmethone
- Otifuril
- Polival
- Sepsinol
- Sistogram
- Spectrafur
- Ultrafur
- Unifur
- Valsyn
- Viofural
Last updated: 19 March 1998